亮氨酸脑啡肽抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 亮氨酸脑啡肽抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Enkephalin and enkephalin-like peptides have been detected in many animal species. In mammals these opioid pentapeptides are cleaved from a common precursor molecule which is expressed in a number of cell types, including neurons and endocrine cells associated with the sympathetic nervous system where they are often co-stored with catecholamines. They are known  亮氨酸脑啡肽抗体to be endogenous ligands for Sopioid receptors and are known to mediate analgesia at the spinal level. Met-enkephalin (tyr-gly-gly-phe-met) and leu-enkephalin (tyr-gly-gly-phe-leu) are pentapeptides which compete with and mimic the effects of opiate drugs. Although interest in enkephalins stems largely from their possible role in the brain, the richest source of these peptides is the adrenal gland. The amino acid sequence shows that the precursor is 267 amino acids long and contains 6 interspersed Met-enkephalin sequences and  亮氨酸脑啡肽抗体1 Leu-enkephalin sequence. The precursor does not contain the sequences of dynorphin, alpha-neo-endorphin or beta-endorphin. (Because of structural similarities it had been postulated that beta-endorphin is precursor of Met-enkephalin, and that dynorphin or alpha-neo-endorphin is precursor of Leu-enkephalin.)

 亮氨酸脑啡肽抗体Also known as:

Met enkephalin; Met enkephalin Arg Gly Leu; Met enkephalin Arg Phe; OGF; Opioid growth factor; PENK; PENKB; Proenkephalin A; Proenkephalin; Proenkephalin B; Synenkephalin; Leucine enkephalin; [5-Leucine] Enkephalin; Enkephalin L; [Leu5]Enkephalin; COLI_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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 亮氨酸脑啡肽抗体Immunogen: KLH conjugated Leu Enkephalin peptide.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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