磷酸化膜相关蛋白酪氨酸激酶Lyn抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化膜相关蛋白酪氨酸激酶Lyn抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Lyn (also known as p53/56 Lyn) is a membrane associated protein tyrosine kinase (PTK) mostly expressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis.磷酸化膜相关蛋白酪氨酸激酶Lyn抗体 A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphorylate Tec on multiple residues. Lyn can also be regulated by IL2 and IL3.

磷酸化膜相关蛋白酪氨酸激酶Lyn抗体Also known as:

Lyn (phospho Y507); Lyn (phospho Tyr507); p-Lyn (Tyr507); Lyn (phospho Y508); Lyn (phospho Tyr508); p-Lyn (Tyr508); Hck 2; JTK 8; JTK8; ONCOGENE LYN; Tyrosine protein kinase LYN; V yes 1 Yamaguchi sarcoma viral related oncogene homolog; Yamaguchi sarcoma viral (v yes 1) related oncogene homolog; AA407514; EC 2.7.10.2; FLJ26625; LYN_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,磷酸化膜相关蛋白酪氨酸激酶Lyn抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Cat, Danio rerio.

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human.

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Predicted Molecular Weight: 57kDa.

磷酸化膜相关蛋白酪氨酸激酶Lyn抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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