肿瘤抑制基因LATS2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 肿瘤抑制基因LATS2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for肿瘤抑制基因LATS2抗体 accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq].

肿瘤抑制基因LATS2抗体Also known as:

Kinase phosphorylated during mitosis; KPM; Large tumor suppressor homolog 2; Large tumor suppressor homolog 2 Drosophila; LATS large tumor suppressor Drosophila homolog 2; LATS large tumor suppressor homolog 2; Serine/threonine kinase kpm; Serine/threonine protein kinase kpm;肿瘤抑制基因LATS2抗体 Warts like kinase; FLJ13161; Kinase phosphorylated during mitosis protein; Large tumor suppressor kinase 2; Lats2; LATS2_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, d,.

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Immunogen: KLH conjugated synthetic peptide derived from human LATS2.

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肿瘤抑制基因LATS2抗体Predicted Molecular Weight: 120kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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