Rho的鸟嘌呤核苷酸交换因子12抗体

Quantity size:

0.2ml

Concentration:

1mg/ml Rho的鸟嘌呤核苷酸交换因子12抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a Rho的鸟嘌呤核苷酸交换因子12抗体complex with G proteins and stimulate Rho-dependent signals. This protein is observed to form myeloid/lymphoid fusion partner in acute myeloid leukemia (from EntrezGene). LARG has also been implicated in linking heterotrimeric G proteins to microtubule organisation in regulation of cell polarity.

Rho的鸟嘌呤核苷酸交换因子12抗体Also known as:

ARHGEF12; KIAA0382; leukemia-associated rho guanine nucleotide exchange factor; Leukemia-associated RhoGEF; PRO2792; Rho guanine exchange factor (GEF) 12; Rho guanine nucleotide exchange factor (GEF) 12; Rho guanine nucleotide exchange factor 12; Similar to Mouse Lsc oncogene; ARHGC_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,Rho的鸟嘌呤核苷酸交换因子12抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human LARG cor.

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Predicted Molecular Weight: 173kDa.

Rho的鸟嘌呤核苷酸交换因子12抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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