可溶性半乳糖凝集素3结合蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 可溶性半乳糖凝集素3结合蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

LGALS3BP is a ligand of galectin 3, and has been suggested to influence tumor proliferation and metastasis formation. Galectins and their ligands have been implicated in cell transformation and cancer metastasis, and found to have prognostic value. LGALS3BP also可溶性半乳糖凝集素3结合蛋白抗体 known as Mac 2 BP,and as 90K, is a highly glycosylated, secreted protein extensively studied in human cancer, which binds galectin 1, galectin 3 and galectin 7. High expression levels of this molecule are associated with a shorter survival, the occurrence of metastasis or a reduced response to chemotherapy in patients with different types of malignancy.可溶性半乳糖凝集素3结合蛋白抗体 The mechanisms underlying the prognostic significance of 90K and galectins in cancer are far from being understood, although they may be related to the ability of these proteins to interact and, to some extent, modulate cell cell and cell matrix adhesion and apoptosis.

可溶性半乳糖凝集素3结合蛋白抗体Also known as:

Mac 2 binding protein; MAC2BP; Tumor associated antigen 90K; 90K; 90K MAC 2 BP; Basement membrane autoantigen p105; Galectin 3 binding protein; L3 antigen; Lectin galactoside binding soluble 3 binding protein; M2BP; Mac 2 BP; Serum protein 90K; LG3BP_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human LGALS3BP.

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可溶性半乳糖凝集素3结合蛋白抗体Predicted Molecular Weight: 63kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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