微管相关蛋白轻链3C抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  微管相关蛋白轻链3C抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein,微管相关蛋白轻链3C抗体 is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. There are three isoforms of human LC3 (named MAP1LC3A, MAP1LC3B, and MAP1LC3C), which exhibit different tissue distributions. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.

微管相关蛋白轻链3C抗体Also known as:

LC3 like protein 2; MAP1 light chain 3 like protein 3; Microtubule-associated proteins 1A/1B light chain 3C; Autophagy-related protein LC3 C; Autophagy-related ubiquitin-like modifier LC3 C; MAP1 light chain 3-like protein 3; MAP1A/MAP1B light chain 3 C; MAP1A/MAP1B LC3 C; Microtubule-associated protein 1 light chain 3 gamma; MAP1LC3C; MLP3C_HUMAN.

Specificity:

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Rabbit Polyclonal IgG微管相关蛋白轻链3C抗体, affinity purified by Protein A.

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Reacts with: Human, Chicken, Dog, Pig, Cow, Daniorerio.

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Immunogen: KLH conjugated synthetic peptide derived from human LC3C(52-.

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Predicted Molecular Weight: 16kDa.

微管相关蛋白轻链3C抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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