含亮氨酸神经胶质瘤失活蛋白4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml含亮氨酸神经胶质瘤失活蛋白4抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

LGI4, also known as leucine-rich glioma-inactivated protein 4, is a 537 amino acid secreted glycosylated protein that is widely expressed, with highest levels found within the nervous system. Interestingly, siRNA knockdown studies of LGI4 expression in Schwann cells含亮氨酸神经胶质瘤失活蛋白4抗体have been shown to result in the inhibition of myelination, thus suggesting that LGI4 is an essential component of myelin formation and axon segregation. LGI4 shares significant homology with its other family members, LGI1, LGI2 and LGI3. Significantly, mutations in the gene encoding LGI1 have been linked to human temporal lobe epilepsy and, given the sequence similarity of LGI4, it is likely that it also may be implicated in the含亮氨酸神经胶质瘤失活蛋白4抗体 pathology of seizures. LGI4 is localized subcellularly to the Golgi, ER and vesicles. There are two isoforms of LGI4 that are produced as a result of alternative splicing events.

含亮氨酸神经胶质瘤失活蛋白4抗体Also known as:

Leucine rich glioma inactivated gene 4; Leucine rich glioma inactivated protein 4; leucine-rich repeat LGI family member 4; Leucine rich repeat LGI family member 4; LGI1 like protein 3; LGI4; Lgi4 protein; Lgil3; LGI4_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human LGI4.

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Predicted Molecular Weight: 57kDa.

含亮氨酸神经胶质瘤失活蛋白4抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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