磷酸化5-脂氧合酶抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化5-脂氧合酶抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are 磷酸化5-脂氧合酶抗体important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. 磷酸化5-脂氧合酶抗体Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Also known as:

5 Lipoxygenase (phospho S524)human mouse; p-5 Lipoxygenase (phospho S524)human mouse; 5 Lipoxygenase (phospho S523)rat; p-5 Lipoxygenase (phospho S523)rat; 5-lipoxygenase; 5 LO; 5LPG;磷酸化5-脂氧合酶抗体 ALOX 5; ALOX5; Arachidonate 5 lipoxygenase; Arachidonic acid 5 lipoxygenase; Leukotriene A4 synthase; LOG 5; LOG5; MGC163204; LOX5_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from rat 5.

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磷酸化5-脂氧合酶抗体Predicted Molecular Weight: 78kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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