淋巴细胞抗原Ly6D抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 淋巴细胞抗原Ly6D抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Ly-6D is a 128 amino acid glycoprotein that is expressed in squamous cell carcinoma cell lines and squamous cell epithelia tissue. Ly-6D contains a signal peptide, 2 theoretical phosphorylation sites and 3 putative myristoylation sites. Upregulation of the gene encoding Ly-6D in head and neck cancers is associated with poor prognosis and high expression 淋巴细胞抗原Ly6D抗体of Ly-6D has been linked to enhanced cell migration. Ly-6D is frequently used as a molecular marker for diagnosis and therapy of head-and-neck squamous cell carcinoma (HNSCC). It has been suggested that Ly-6D may regulate the expression levels of certain fucosylated E-selectin ligands and protein FX, a protein that contributes to the last step in the synthesis of GDP-L-fucose, in HNSCC cell lines. This finding is indicative that Ly-6D may regulate tumor cell adhesion in inflamed vessel walls that express E-selectin.

淋巴细胞抗原Ly6D抗体Also known as:

E48 antigen; LY 6D; LY-6D;Lymphocyte antigen 6 complex; LY6D_HUMAN; Lymphocyte antigen 6 complex locus D; Lymphocyte antigen D; Lymphocyte antigen 6D.

Specificity:

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Rabbit Polyclonal IgG, 淋巴细胞抗原Ly6D抗体affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthetic peptide derived from human LY6D.

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淋巴细胞抗原Ly6D抗体Predicted Molecular Weight: 8.4kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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