低密度脂蛋白受体相关蛋白1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 低密度脂蛋白受体相关蛋白1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Low density lipoprotein receptor-related protein (also known as low density LRP, LRP1, alpha-2-macroglobulin receptor or Apolipoprotein E receptor) is an endocytotic receptor that is involved both in endocytosis and in phagocytosis of apoptotic cells. It is required for early embryonic development, is involved in cellular lipid homeostasis, 低密度脂蛋白受体相关蛋白1抗体and may play a role in APP metabolism, kinase-dependent intracellular signalling, neuronal calcium signalling and neurotransmission. Low density LRP also plays a role in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha-2-macroglobulin), and is involved in the local metabolism of complexes of plasminogen activators and their endogenous ligands. Low density LPR is postulated to be one of the major players in host resistance to HIV. The precursor low density LRP molecule is cleaved post-translationally to form a 85 kDa membrane-spanning subunit (LRP-85) and a 515 kDa large extracellular domain (LRP-515), which remains non-covalently associated with LRP-85. Following cleavage, the intracellular domain (LPRICD) is present in both the cytoplasm and the nucleus.

低密度脂蛋白受体相关蛋白1抗体Also known as:

A2MR; Alpha 2 macroglobulin receptor; alpha 2MR; APOER; Apolipoprotein E receptor; APR; CD 91; CD91; CD91 antigen; Low density lipoprotein receptor related protein 1; Low density lipoprotein related protein 1; LRP 1; LRP 515; LRP 85; LRP; LRP ICD; LRP1; LRP1 protein; LRP515.

Specificity:

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Rabbit Polyclonal IgG, 低密度脂蛋白受体相关蛋白1抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human LRP1.

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Predicted Molecular Weight: 500kDa.

低密度脂蛋白受体相关蛋白1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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