供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL0924R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml v-maf 肌腱膜纤维肉瘤癌基因同源物A抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Insulin gene expression is regulated by several islet-enriched transcription factors. However, MAFA is the only beta cell-specific activator. MAFA selectively induces endogenous insulin transcription in non-beta cells. MAFA was also first detected in the insulin-producing v-maf 肌腱膜纤维肉瘤癌基因同源物A抗体cells formed during the second and predominant phase of beta cell differentiation, and absent in the few insulin-positive cells found in Nkx6.1(-/-) pancreata, which lack the majority of second-phase beta cells. These results demonstrate that MAFA is a potent insulin activator that is likely to function downstream of Nkx6.1 during islet insulin-producing cell development.
v-maf 肌腱膜纤维肉瘤癌基因同源物A抗体Also known as:
Mafa homolog; V-maf musculoaponeurotic fibrosarcoma oncogene homolog A; Pancreatic beta-cell-specific transcriptional activator;(avian)(V-maf musculoaponeurotic fibrosarcoma oncogene homolog A; MAFA_MOUSE.
Specificity:
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Rabbit Polyclonal IgGv-maf 肌腱膜纤维肉瘤癌基因同源物A抗体, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, .
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Immunogen: KLH conjugated synthetic peptide derived from mouse Mafa.
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Predicted Molecular Weight: 37kDa.
v-maf 肌腱膜纤维肉瘤癌基因同源物A抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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