丝裂原活化蛋白激酶活化的蛋白激酶2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  丝裂原活化蛋白激酶活化的蛋白激酶2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

MAP kinase activated protein kinase 2 (MAPKAP Kinase 2), also known as p45 hsp27 kinase, is a 45-54 kDa serine/threonine protein kinase that contains a proline rich sequence and two putative SH3 binding sites. MAPKAP Kinase 2 is activated in response to stress, IL1 and TNF,丝裂原活化蛋白激酶活化的蛋白激酶2抗体 possibly catalyzed by p38/Hog dependent phosphorylation. One of the major substrates of MAPKAP Kinase 2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. MAPKAP2 is implicated in several disorders including ischemic brain injury and heart failure and has丝裂原活化蛋白激酶活化的蛋白激酶2抗体 been shown to be important in regulating stress resistance and the production of TNF alpha.

丝裂原活化蛋白激酶活化的蛋白激酶2抗体Also known as:

MAP Kinase Activated Protein Kinase 2; MAPK activated protein kinase 2; MAPKAP kinase 2; MAPKAPK 2; MAPKAPK2; Mitogen Activated Protein Kinase Activated Protein Kinase 2; MK 2; MK2; MAPK2_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human MAPKAP Kinase 2.

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Predicted Molecular Weight: 44kDa.

丝裂原活化蛋白激酶活化的蛋白激酶2抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:10-200  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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