磷酸化丝裂原活化蛋白激酶活化的蛋白激酶2抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化丝裂原活化蛋白激酶活化的蛋白激酶2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

MAP kinase activated protein kinase 2 (MAPKAP Kinase 2), also known as p45 hsp27 kinase, is a 45-54 kDa serine/threonine protein kinase that contains a proline rich sequence and two putative SH3 binding sites. MAPKAP Kinase 2 is activated in response to stress, IL1 and TNF, possibly catalyzed by p38/Hog dependent phosphorylation. One of the磷酸化丝裂原活化蛋白激酶活化的蛋白激酶2抗体 major substrates of MAPKAP Kinase 2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. MAPKAP2 is implicated in several disorders including ischemic brain injury and heart failure and has been shown to be important in regulating stress resistance and the production of TNF alpha.

磷酸化丝裂原活化蛋白激酶活化的蛋白激酶2抗体Also known as:

MAPKAP Kinase 2 (phospho S222); p-MAPKAP Kinase 2 (phospho S222); 3PK; AA960234; MAP kinase activated protein kinase 2; MAP kinase activated protein kinase 3; MAPK activated protein kinase 2; MAPK activated protein kinase 3; MAPKAP kinase 2; MAPKAP kinase 3; MK2; MK3; MAPK2_HUMAN; OTTHUMP00000034531; Rps6kc1.

Specificity:

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Rabbit Polyclonal IgG,磷酸化丝裂原活化蛋白激酶活化的蛋白激酶2抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Rabbit, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human MAPKAPK2 around the phosphorylation site of Thr222.

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Predicted Molecular Weight: 46kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

磷酸化丝裂原活化蛋白激酶活化的蛋白激酶2抗体Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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