磷酸化蛋白激酶MST抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化蛋白激酶MST抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

MST1/STK4 encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible 磷酸化蛋白激酶MST抗体 that this protein induces the chromatin condensation observed in this process. [provided by RefSeq]. 
MST2/STK3, Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996[PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM].

磷酸化蛋白激酶MST抗体 Also known as:

MST1/MST2 (phospho T183 + T180); MST1/MST2 (phospho T183); MST1/MST2 (phospho Thr183); Kinase responsive to stress; Krs2; Mammalian STE20 like protein kinase 1; Mammalian STE20-like protein kinase 1; Mammalian sterile 20 like 1; MST-1; Serine/threonine kinase 4; Serine/threonine protein kinase Krs 2; Serine/threonine-protein kinase 4; Serine/threonine-protein kinase Krs-2; STE20 like kinase MST1; Serine/threonine-protein磷酸化蛋白激酶MST抗体  kinase 4 18kDa subunit; Serine/threonine-protein kinase 4 37kDa subunit; STE20-like kinase MST1; STK4; STK4_HUMAN; MST1/N; MST1/C; TIIAC; YSK3.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Mst1 around the phosphorylation site of Thr183.

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Predicted Molecular Weight: 19/37/56kDa.

磷酸化蛋白激酶MST抗体 Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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