磷酸化丝裂原活化蛋白激酶MAP4K4抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化丝裂原活化蛋白激酶MAP4K4抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 磷酸化丝裂原活化蛋白激酶MAP4K4抗体kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.

磷酸化丝裂原活化蛋白激酶MAP4K4抗体Also known as:

MAP4K4(phospho S629); p-MAP4K4(phospho S629); Hepatocyte progenitor kinase like/germinal center kinase like kinase; HGK; HPK/GCK like kinase; HPK/GCK like kinase HGK; KIAA0687; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; Mitogen activated protein kinase kinase kinase kinase 4; Nck interacting kinase; NIK.

Specificity:

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Rabbit Polyclonal IgG, 磷酸化丝裂原活化蛋白激酶MAP4K4抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser629.

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Predicted Molecular Weight: 142kDa.

磷酸化丝裂原活化蛋白激酶MAP4K4抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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