髓系/淋巴混合谱系白血病蛋白5抗体

uantity size:

0.2ml

Concentration:

1mg/ml 髓系/淋巴混合谱系白血病蛋白5抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

MLL5 is a divergent member of the Drosophila Trithorax related SET and PHD domain containing chromatin regulators that are involved in the regulation of transcriptional "memory" during differentiation. Human MLL5 is located on chromosome 7q22, that is frequently 髓系/淋巴混合谱系白血病蛋白5抗体deleted in myeloid leukemias. Inactivation of the Mll5 gene in mice results in a reduction in the average representation of hematopoietic stem cells, and in functional impairment of long term hematopoietic repopulation potential under competitive conditions. Overexpression of the protein also inhibits cell cycle progression.This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with 髓系/淋巴混合谱系白血病蛋白5抗体an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized.

髓系/淋巴混合谱系白血病蛋白5抗体Also known as:

HDCMC04P; Histone lysine N methyltransferase MLL5; KMT2E; Lysine N methyltransferase 2E; Myeloid/lymphoid or mixed lineage leukemia 5 (trithorax homolog, Drosophila); Myeloid/lymphoid or mixed lineage leukemia 5; Myeloid/lymphoid or mixed lineage leukemia protein 5; MLL5_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human MLL5.

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髓系/淋巴混合谱系白血病蛋白5抗体Predicted Molecular Weight: 205kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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