磷酸化p38调节/激活蛋白激酶抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化p38调节/激活蛋白激酶抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The serine/threonine kinase PRAK is activated in response to cellular stress and proinflammatory cytokines, through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38 alpha, and MAPK11/p38 beta. PRAK has been reported to have a putative tumor suppressor function磷酸化p38调节/激活蛋白激酶抗体 by mediating senescence upon activation by p38 in response to oncogenic ras. It is thought that phosphorylation of p53 by PRAK following activation of p38 MAPK by ras plays an important role in ras induced senescence and tumor suppression.

磷酸化p38调节/激活蛋白激酶抗体Also known as:

p-PRAK(phospho Thr182); MAPKAPK5(phospho T182); MAP kinase-activated protein kinase 5; MAPKAP kinase 5; MAPKAPK5; mitogen-activated protein kinase-activated protein kinase 5; p38-regulated/activated protein kinase.

Specificity:

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Rabbit Polyclonal IgG磷酸化p38调节/激活蛋白激酶抗体, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human MAPKAPK5 around the phosphorylation site of Thr182.

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Predicted Molecular Weight: 52kDa.

磷酸化p38调节/激活蛋白激酶抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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