供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL6412R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 巨噬细胞甘露糖受体2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate 巨噬细胞甘露糖受体2抗体protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix co-operating with the matrix metalloproteinases (MMPs).
巨噬细胞甘露糖受体2抗体Also known as:
C-type lectin domain family 13 member E; C-type mannose receptor 2; CD 280; CD280; CD280 antigen; CLEC 13E; CLEC13E; ENDO 180; Endocytic receptor (macrophage mannose receptor family); Endocytic receptor 180; FLJ35911; KIAA0709; Macrophage mannose receptor 2; Mannose receptor C type 2; MRC 2; MRC2; MRC2_HUMAN; UPAR-associated protein; UPARAP; Urokinase plasminogen activator receptor associated protein; Urokinase receptor associated巨噬细胞甘露糖受体2抗体 protein; Urokinase receptor-associated protein; Urokinase-type plasminogen activator receptor-associated protein.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human MRC2/CD280.
●
巨噬细胞甘露糖受体2抗体Predicted Molecular Weight: 167kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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