供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL4705R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 肌球蛋白轻链激酶抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms.肌球蛋白轻链激酶抗体 In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four肌球蛋白轻链激酶抗体 transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq].
Also known as:
myosin light chain kinase; DKFZp686I10125; EC 2.7.11.18; FLJ12216; Kinase related protein; KRP; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; MYLK; MYLK1; Myosin light chain kinase smooth muscle and non muscle isozymes; Myosin light polypeptide kinase; OTTHUMP00000180642;肌球蛋白轻链激酶抗体 OTTHUMP00000180643; smMLCK; Smooth muscle myosin light chain kinase; Telokin; deglutamylated form; MLCK; MYLK_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, Guinea Pig, .
●
Immunogen: KLH conjugated synthetic peptide derived from human MLCK.
●
肌球蛋白轻链激酶抗体Predicted Molecular Weight: 210kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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