DNA修复甲基磺酸敏感性基因19抗体

Quantity size:

0.2ml

Concentration:

1mg/ml DNA修复甲基磺酸敏感性基因19抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

MMS19 is a 1,030 amino acid nuclear protein containing seven HEAT repeats that belongs to the MET18/MMS19 family. Via its interactions with TFIIH p80 and TFIIH p89 helicases, MMS19 plays a roleDNA修复甲基磺酸敏感性基因19抗体 in nucleotide excision repair (NER) and RNA polymerase II (Pol II) transcription. MMS19 may also function as a transcriptional coactivator of estrogen receptor. While ubiquitously expressed, highest levels of MMS19 have been found in testis. At least five distinct MMS19 protein isoforms exist, which are produced by alternative splicing events. The gene encoding MMS19 maps to human chromosome 10q24.1, and is associated with the risk of pancreatic cancer.

DNA修复甲基磺酸敏感性基因19抗体Also known as:

MET18MMS19 nucleotide excision repair homolog; methyl methanesulfonate sensitivity gene19; MMS19L; MMS-19L; MMS 19 nucleotide excision repair homolog MET18.

Specificity:

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Rabbit Polyclonal IgG,DNA修复甲基磺酸敏感性基因19抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human MMS 19.

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DNA修复甲基磺酸敏感性基因19抗体Predicted Molecular Weight: 113kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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