磷酸化丝裂原活化蛋白激酶磷酸酶1抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化丝裂原活化蛋白激酶磷酸酶1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of磷酸化丝裂原活化蛋白激酶磷酸酶1抗体 vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues.

磷酸化丝裂原活化蛋白激酶磷酸酶1抗体Also known as:

P-MKP1(Ser318); Mitogen activated protein kinase phosphatase 1; CL 100; CL100; Dual Specificity Phosphatase 1; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; DUSP 1; EC 3.1.3.16; EC 3.1.3.48; HVH 1; HVH1; MAP kinase phosphatase 1; MKP 1; MKP1; MKP-1; Protein tyrosine phosphatase CL100; PTPN 10; PTPN10; Serine/threonine specific protein phosphatase; VH 1; VH1; 3ch134; Mkp1; Ptpn16.

Specificity:

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Rabbit Polyclonal IgG,磷酸化丝裂原活化蛋白激酶磷酸酶1抗体 affinity purified by Protein A.

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Reacts with: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human MKP1 around the phosphorylation site of Ser318.

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Predicted Molecular Weight: 40kDa.

磷酸化丝裂原活化蛋白激酶磷酸酶1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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