供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL7135R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 锌指蛋白801抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The Myc-associated zinc finger protein MAZ is a transcription factor that participates in both the initiation and termination of transcription of target genes. MAZ functions as a true transcriptional repressor in that it represses transcription independent of the c-Myc promoter. Both MAZ and SP1 bind to the parathyroid hormone (PTH)/ PTH-related peptide receptor promoter, thereby influencing the cell-specific锌指蛋白801抗体 expression of its gene product. MAZ and SP1 also regulate expression from the serotonin 1A receptor gene promoter, suggesting that MAZ may act on a variety of promoters through G-C rich sequences, which serve as binding sites for the SP1 family of transcription factors. Competition between SP1 and MAZ control tissue-specific expression of the PNMT gene. The interaction 锌指蛋白801抗体of MAZ with the transcriptional repressor FAC1 may affect gene regulation in neurodegeneration. MAZ also acts as a growth suppressor protein, in part by affecting the levels of key cell cycle regulatory proteins such as cyclin A and E.
Also known as:
MAZ_HUMAN; Myc-associated zinc finger protein; MAZI; Purine-binding transcription factor; Serum amyloid A-activating factor-1; SAF-1; Transcription factor Zif87; ZF87; Zinc finger protein 801; MAZ; Pur-1; PUR1; SAF-1; SAF-2; SAF-3; ZF87; Zif87; ZNF801.
Specificity:
●
Rabbit Polyclonal IgG, 锌指蛋白801抗体affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, .
●
Immunogen: KLH conjugated synthetic peptide derived from human MAZ.
●
Predicted Molecular Weight: 53kDa.
锌指蛋白801抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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