GTP结合蛋白7抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  GTP结合蛋白7抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

MTH1 is a 179 amino acid cytoplasmic protein that is a member of the nudix hydrolase family. Highly expressed in testis, thymus and proliferating blood lymphocytes, MTH1 functions as an antimutagenic that hydrolyzes oxidized purine nucleoside triphosphates to their corresponding monophosphates. Through its ability to enzymatically hydrolyze ATP and GTP to AMP and GMP, respectively, MTH1 prevents misincorporation of GTP into DNA, GTP结合蛋白7抗体thus preventing A:T to C:G transversions. The cytoplasmic location of MTH1, along with its antimutagenic capabilities, suggests that it may also be involved in the sanitization of nucleotide pools for both mitochondrial and nuclear genomes. Four isoforms of MTH1 exist—three of which are formed due to alternative splicing events and one of which is formed via a single-nucleotide polymorphism. Overexpression of MTH1 is implicated in prostate and cell lung carcinomas

GTP结合蛋白7抗体Also known as:

GTP; GTP binding protein; GTP binding protein 7 (putative); GTP binding protein 7; GTP-binding protein 7 (putative); GTP-binding protein 7; GTPBP7; Mitochondrial GTPase 1; mitochondrial GTPase 1 homolog (S. cerevisiae); MTG1; MTG1_HUMAN; OTTHUMP00000020814; OTTHUMP00000046565; RP11 108K14.2; RP11-108K14.2; RP11108K14.2.

Specificity:

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Rabbit Polyclonal IgG, GTP结合蛋白7抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Cow, .

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Immunogen: KLH conjugated synthetic peptide derived from human MTG1/GTPBP7.

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Predicted Molecular Weight: 37kDa.

GTP结合蛋白7抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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