中胚层诱导早期反应蛋白3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 中胚层诱导早期反应蛋白3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The mesoderm induction early response (MIER) protein family (also known as the fibroblast growth factor (FGF)-regulated immediate-early protein family) comprises a group of proteins that are activated by FGF (fibroblast growth factor). This suggests that MEIR proteins may play a significant role in FGF-regulated cellular activities and in the progression of中胚层诱导早期反应蛋白3抗体 certain cancers. MIER proteins contain one SANT domain, which is involved in transcriptional activation and repression, and one ELM2 domain, which was first characterized in egl-27, a gene that is critically involved in embryonic patterning of C. elegans. MIER1, formerly known as early response 1 (ER1), was first cloned and characterized in Xenopus.中胚层诱导早期反应蛋白3抗体 Expression of MIER1 is negligible in most normal tissues, but has been found to be upregulated in breast carcinoma cell lines and tumors. MIER1 functions as a transcriptional repressor of a number of genes including Sp1 target genes, most likely through interaction with HDAC1.

Also known as:

DKFZp686L09111; DKFZp781G1119; DKFZP781I1119; FLJ35954; Mesoderm induction early response 1 family member 3; Mesoderm induction early response protein 3; Mi-er3; MIER 3; MIER3; MIER3_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, 中胚层诱导早期反应蛋白3抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Ferret, Baboon, Rhesus monkey, Gorilla, Orangutan.

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Immunogen: KLH conjugated synthetic peptide derived from human MIER3.

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Predicted Molecular Weight: 61kDa.

中胚层诱导早期反应蛋白3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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