磷酸化细胞核因子p50/k基因结合核因子抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化细胞核因子p50/k基因结合核因子抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus 磷酸化细胞核因子p50/k基因结合核因子抗体and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

磷酸化细胞核因子p50/k基因结合核因子抗体Also known as:

NFkB p105 / p50 (phospho S927); p-NFkB p105 / p50 (phospho S927); DKFZp686C01211; DNA binding factor KBF1; DNA binding factor KBF1 EBP1; DNA binding factor KBF1 EBP1; DNA-binding factor KBF1; EBP 1; EBP-1; EBP1; KBF1; MGC54151; NF kappa B; NF kappabeta; NF kB1; NFKB 1; NFKB p105; NFKB p50; NFKB1; Nuclear factor kappa B DNA binding subunit; Nuclear factor NF kappa B p105 subunit; Nuclear factor NF kappa B p50 subunit; Nuclear factor NF-kappa-B p50 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1;磷酸化细胞核因子p50/k基因结合核因子抗体 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p84/NF-kappa-B1 p98; NFKB1_RAT.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Rat, Hamster, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from rat NF-KappaB p105 around the phosphorylation site of Ser927.

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磷酸化细胞核因子p50/k基因结合核因子抗体Predicted Molecular Weight: 105kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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