供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL11214R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 神经束蛋白186抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Nfasc186 (Neurofascin 186) is one of two alternatively spliced products of the Neurofascin (Nfasc) gene in rat; the other being Nfasc155. The establishment of paranodal axoglial junctions in myelinated nerves where voltage-gated sodium channels are concentrated at the nodes of Ranvier is determined by myelin-forming glia. The two isoforms of Neurofascin,神经束蛋白186抗体 Nfasc186 in neurons and Nfasc155 in glia, are required for the assembly of these specialized domains. These two major Neurofascins play essential roles in assembling the nodal and paranodal domains of myelinated axons and are essential for the transition to saltatory conduction in developing vertebrate nerves. Nfasc186 (Isoform 1) is expressed at the Nodes of Ranvier while the Nfasc155 (isoforms 2 and 3) are expressed in unmyelinated axons.
神经束蛋白186抗体Also known as:
Neurofascin; NF antibody NF186; NFASC; NRCAML; NFASC_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG,神经束蛋白186抗体 affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Horse, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Nfasc186 .
●
Predicted Molecular Weight: 147kDa.
神经束蛋白186抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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