硝基化α-突触核蛋白

Quantity size:

0.2ml

Concentration:

1mg/ml 硝基化α-突触核蛋白  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The synuclein family members, including Alpha-synuclein (also designated NACP for non-Beta-Amyloid component) and Beta-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. Alpha-synuclein is localized to neuronal cell bodies and synapses. Alpha-synuclein was first identified as硝基化α-突触核蛋白 a component of Alzheimer’s disease amyloid plaques. Abnormal platelet function in Alzheimer’s disease has been demonstrated. During megakaryocytic differentiation Alpha-synuclein has been found to be upregulated, while Beta-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of Alpha-synuclein has been found in patients with early onset Parkinson’s disease.

硝基化α-突触核蛋白Also known as:

SYUA_HUMAN; nitrated Alpha-synuclein (nitrated-Tyr39); nitrated Alpha-synuclein (nitro-Tyr39); Alpha-synuclein (nitro-Tyr39); Alpha-synuclein (nitro Tyr39); nitrated Alpha synuclein; nitrated Alpha-Synuclein; Alpha synuclein; Alpha-synuclein, isoform NACP140; alphaSYN; MGC105443; MGC110988; MGC127560; MGC64356; NACP; Non A beta component of AD amyloid; Non A4 component of amyloid precursor; Non-A-beta component of alzheimers 硝基化α-突触核蛋白disease amyloid , precursor of; PARK 1; PARK 4; PARK1; PARK4; Parkinson disease familial 1; PD 1; PD1; SNCA; Snca synuclein, alpha (non A4 component of amyloid precursor); Synuclein alpha; Synuclein, alpha (non A4 component of amyloid precursor).

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, .

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Immunogen: KLH conjugated Synthesised nitrylpeptide derived from human Alpha-synuclein around the nitrosation site of Tyr39.

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硝基化α-突触核蛋白Predicted Molecular Weight: 15kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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