跨膜硫酸软骨素蛋白聚糖C抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 跨膜硫酸软骨素蛋白聚糖C抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Neuroglycan C is a brain-specific chondroitin sulfate proteoglycan (CSPG) implicated in the proliferation of neural stem and progenitor cells. Neuro-glycan C is a single-pass membrane protein that can manifest as a part-time proteoglycan depending on the tissue expressing it. In its proteoglycan form, Neuroglycan C exhibits chondroitin sulfate glycans and functions as a receptor for midkine, a growth factor that binds heparin, to 跨膜硫酸软骨素蛋白聚糖C抗体affect cytoskeletal changes. By means of ectodomain shedding, the ectodomain of Neuroglycan C is able to enhance neurite outgrowth from neurons. Neurite growth stimulation is affected by both an EGF-like and an acidic amino acid domain found on the shed ectodomain.跨膜硫酸软骨素蛋白聚糖C抗体 Both domains instigate neurite growth, however, these domains exhibit differing functionality as to number of neurites produced and neuron types stimulated.

跨膜硫酸软骨素蛋白聚糖C抗体Also known as:

Acidic leucine rich EGF like domain containing brain protein; Acidic leucine-rich EGF-like domain-containing brain protein; Caleb; CSPG5_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human Neuroglycan C.

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Predicted Molecular Weight: 57kDa.

跨膜硫酸软骨素蛋白聚糖C抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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