神经肿瘤Nova2抗原抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 神经肿瘤Nova2抗原抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Nova-1 and Nova-2 are members of a superfamily of protein regulators of RNA metabolism in neurons. Both are nuclear RNA binding proteins with K homology motifs, conserved protein sequences which bind to RNA (1,2). Nova proteins, normally sequestered in the central 神经肿瘤Nova2抗原抗体  nervous system, are expressed by systemic tumors in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia (POMA) (3,4). Nova-1 is expressed in the hindbrain and ventral spinal cord and Nova-2 is expressed in the neocortex and hippocampus (4). Nova-1 is necessary for regulating neuron-specific alternative splicing of the glycine receptor Alpha2 pre-mRNA (5).

 神经肿瘤Nova2抗原抗体 Also known as:

ANOVA; Astrocytic NOVA1 like RNA binding protein; Gm1424; NOVA2_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,  神经肿瘤Nova2抗原抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human Nova2.

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Predicted Molecular Weight: 49kDa.

 神经肿瘤Nova2抗原抗体 Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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