供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL11421R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml G蛋白偶联受体FM4/神经调节肽U受体2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein G蛋白偶联受体FM4/神经调节肽U受体2抗体coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It’s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system G蛋白偶联受体FM4/神经调节肽U受体2抗体with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.
G蛋白偶联受体FM4/神经调节肽U受体2抗体Also known as:
FM4; G protein coupled receptor FM 4; G protein coupled receptor TGR 1; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; Neuromedin U receptor 2; Neuromedin-U receptor 2; NMU R2; NMU-R2; NMU2R; NMUR2; NMUR2_HUMAN; TGR1; GPR-FM4
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Pig, Cow, Horse, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human NMUR2 (181-230aa).
●
G蛋白偶联受体FM4/神经调节肽U受体2抗体Predicted Molecular Weight: 46kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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