CD244自然杀伤细胞受体2B4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml CD244自然杀伤细胞受体2B4抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Natural killer (NK) cells are bone marrow-derived lymphocytes that can kill certain tumor cells and virally infected cells. There are multiple immunoglobulin superfamily (IgSF) receptor-ligand interactions that coordinate NK cell recognition of target cells and cytolytic function. The IgSF receptor NK 2B4 (CD244) is a ligand for CD48 that is expressed onCD244自然杀伤细胞受体2B4抗体 the surface of all mouse and human NK cells and the subset of T cells that mediate NK-like killing. NK 2B4 is a cell surface glycoprotein of the immunoglobulin superfamily that is involved in the regulation of natural killer and T lymphocyte function. NK 2B4 binds the Src homology 2 domain-containing protein (SH2D1A) or signaling lymphocyte activation moleculeCD244自然杀伤细胞受体2B4抗体 (SLAM)-associated protein (SAP), which may function as regulators of NK 2B4-associated signal transduction pathways. NK 2B4 is expressed in human spleen, peripheral blood leukocytes, lymph node, bone marrow and fetal liver.

CD244自然杀伤细胞受体2B4抗体Also known as:

2b4 cDNA 2B4; Cd244; CD244 natural killer cell receptor 2B4; Natural killer cell receptor 2B4; NK cell receptor 2B4; NKR2B4; CD244_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human NKR2B4.

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CD244自然杀伤细胞受体2B4抗体Predicted Molecular Weight: 39kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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