EGR1结合蛋白1抗体

Quantity size:

0.2ml

Concentration:

1mg/mlEGR1结合蛋白1抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2, are corepressors of Egr1/NGFI-A. Both NAB1 and NAB2 contain an amino-terminal NAB-conserved domain 1 (NCB1), EGR1结合蛋白1抗体which is required for binding NGFI-A, and a carboxy-terminal NCD2, which is responsible for the repressor function of NAB proteins. NAB1 requires NGFI-A to gain access to DNA, indicating that NAB1 is an active repressor that works by a direct mechanism. NAB1, which is constitutively expressed, is localized exclusively in the nucleus and may play a role in controlling processes such as cell division, differentiation and apoptosis.

EGR1结合蛋白1抗体Also known as:

EGR 1 binding protein 1; EGR-1-binding protein 1; EGR1 binding protein 1; NAB1; NAB1_HUMAN; NGFI A binding protein 1 (EGR1 binding protein 1); NGFI A binding protein 1; NGFI-A-binding protein 1; Transcriptional regulatory protein p54.

Specificity:

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Rabbit Polyclonal IgG,EGR1结合蛋白1抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human NAB1.

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Predicted Molecular Weight: 54kDa.

EGR1结合蛋白1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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