供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL19255R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 新型抑癌蛋白Nischarin抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin. In humans, this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin新型抑癌蛋白Nischarin抗体 from the cell membrane to endosomes. Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis; possibly by limiting the expression of alpha-5 integrin. In human cardiac tissue, this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation.新型抑癌蛋白Nischarin抗体 Alternative splicing results in multiple transcript variants encoding differerent isoforms. Some isoforms lack the expected C-terminal domains of a functional imidazoline receptor. [provided by RefSeq, Jan 2013]
Also known as:
FLJ14425; FLJ40413; FLJ90519; I 1; I 1 receptor candidate protein; I1R candidate protein; Imidazoline 1 receptor candidate protein; Imidazoline receptor 1; NISCH_HUMAN; Imidazoline receptor新型抑癌蛋白Nischarin抗体 antisera selected; Imidazoline receptor antisera selected protein; Imidazoline receptor candidate; IR1; IRAS; KIAA0975; Nischarin.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, .
●
Immunogen: KLH conjugated synthetic peptide derived from human NISCH.
●
新型抑癌蛋白Nischarin抗体 Predicted Molecular Weight: 167kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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kl062Po01白介素16(IL16)多克隆抗体Polyclonal Antibody to Interleukin 16 (IL16)
kl062Ra01白介素16(IL16)多克隆抗体Polyclonal Antibody to Interleukin 16 (IL16)
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