磷酸化细胞核因子/k基因结合核因子p100抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化细胞核因子/k基因结合核因子p100抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

NFkB is formed through the association of multiple subunits, either as a homodimer or heterodimer. Subunits have been identified as p50 (NFkB1), p65 (RelA), c-Rel, RelB and p52 (NFkB2). The classic NFkB form exists as a p50-p65 heterodimer and predominates in many cell types. Many of the possible combinatorial forms of homo- and heterodimers have been identified and growing evidence indicates that different forms of NFkB have different functions in cells. Interestingly, both the p50 and p52 subunits are derived from the磷酸化细胞核因子/k基因结合核因子p100抗体 precursor proteins p105 and p100 respectively, that each contain multiple copies of the so called ankyrin repeat at their C termini. Nuclear translocation of NFkB is confirmed by the use of electrophorectic mobility shift assays or by immunoblotting with nuclear extracts. The subunit composition of NFkB is confirmed by the use of antibodies that "supershift" the DNA/protein complex.

磷酸化细胞核因子/k基因结合核因子p100抗体Also known as:

NFKB2(phospho S866/S870); NFKB2(phospho S866 + S870); NFKB2(phospho Ser866/Ser870); p-NFKB2(S866/S870); p-NFKB2(Ser866/Ser870); DNA binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10; Lyt10; Oncogene Lyt 10; DNA binding factor KBF2; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10; Lymphocyte translocation chromosome 10 protein; Lyt 10; Lyt10; NFKB2; NFKB2_HUMAN; Nuclear factor NF kappa B p100 subunit; Nuclear factor NF kappa B p52 subunit; Nuclear factor NF-kappa-B p52 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 2; 磷酸化细胞核因子/k基因结合核因子p100抗体Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; Oncogene Lyt 10; Oncogene Lyt-10; p49/p100.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human NFKB2 around the phosphorylation site of Ser866 + Ser870.

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磷酸化细胞核因子/k基因结合核因子p100抗体Predicted Molecular Weight: 100kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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