精神发育迟滞相关蛋白Oligophrenin-1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 精神发育迟滞相关蛋白Oligophrenin-1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Ras p21 can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (1,2). Interaction of Ras p21 with GTPase activating protein (GAP) can increase the rate of hydrolysis of Ras p21-bound GTP by as much as 1000-fold (3). In mitogenically activated and tyrosine kinase-transformed cells, Ras GAP forms a complex with a精神发育迟滞相关蛋白Oligophrenin-1抗体 protein designated p190 (4). At its amino terminus, p190 contains sequence motifs characteristic of all known GTPases, whereas the carboxy terminus contains sequences similar to those found in the Bcr gene product, n-chimerin and Rho GAP, all of which exhibit intrinsic GAP activity (4,5). Oligophrenein-1 is an additional protein with精神发育迟滞相关蛋白Oligophrenin-1抗体 GTPase activating activity. Oligophrenein-1 is a RhoGAP protein that stimulates GTP hydrolysis of Rho subfamily members and is involved in cell migration, morphogenesis and axon outgrowth (6).

Also known as:

Oligophrenin1; Oligophrenin-1; OPHN1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,精神发育迟滞相关蛋白Oligophrenin-1抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from huamn Oligophrenin 1 (418-465aa).

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精神发育迟滞相关蛋白Oligophrenin-1抗体Predicted Molecular Weight: 92kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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