鸟氨酸氨基转移酶抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 鸟氨酸氨基转移酶抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

OAT (ornithine aminotransferase (mitochondrial), ornithine-oxo-acid aminotransferase) is a 439 amino acid protein encoded by the human gene OAT. OAT belongs to the class III pyridoxal-phosphate-dependent aminotransferase family and is usually found as a homotetramer in the mitochondrion matrix. OAT catalyzes the major catalytic reaction for ornithine. Ornithinemia, presumably due to deficiency of ornithine ketoacid aminotransferase (OAT) has been found in patients with gyrate atrophy of the choroid and retina.鸟氨酸氨基转移酶抗体  The clinical history of gyrate atrophy is usually night blindness that begins in late childhood, accompanied by sharply demarcated circular areas of chorioretinal atrophy. During the second and third decades the areas of atrophy enlarge. The hepatic cleavage product, hepatic OAT, is formed by cleaving a 25 amino acid transit peptide from the N-terminus of the OAT precursor. The renal form is produced by cleaving a 35 amino acid transit peptide from the N-terminus。

鸟氨酸氨基转移酶抗体 Also known as:

GACR; Gyrate atrophy; HOGA; OAT_HUMAN; Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form; OAT; OATASE; OKT; Ornithine aminotransferase (gyrate atrophy); Ornithine aminotransferase mitochondrial; ornithine aminotransferase precursor; Ornithine aminotransferase, mitochondrial precursor; Ornithine delta aminotransferase; Ornithine oxo acid aminotransferase.

Specificity:

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Rabbit Polyclonal IgG, 鸟氨酸氨基转移酶抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human ornithine aminotransferase.

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鸟氨酸氨基转移酶抗体 Predicted Molecular Weight: 45kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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