精神发育迟滞相关蛋白Oligophrenin-1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 精神发育迟滞相关蛋白Oligophrenin-1抗体  Buffer = Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

Background:

Ras p21 can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (1,2). Interaction of Ras p21 with GTPase activating protein (GAP) can increase the rate of hydrolysis of Ras p21-bound GTP by as much as 1000-fold (3). In mitogenically精神发育迟滞相关蛋白Oligophrenin-1抗体 activated and tyrosine kinase-transformed cells, Ras GAP forms a complex with a protein designated p190 (4). At its amino terminus, p190 contains sequence motifs characteristic of all known GTPases, whereas the carboxy terminus contains sequences similar to those found精神发育迟滞相关蛋白Oligophrenin-1抗体 in the Bcr gene product, n-chimerin and Rho GAP, all of which exhibit intrinsic GAP activity (4,5). Oligophrenein-1 is an additional protein with GTPase activating activity. Oligophrenein-1 is a RhoGAP protein that stimulates GTP hydrolysis of Rho subfamily members and is involved in cell migration, morphogenesis and axon outgrowth (6).

精神发育迟滞相关蛋白Oligophrenin-1抗体Also known as:

Oligophrenin1; Oligophrenin-1; OPHN1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human Oligophrenin 1.

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精神发育迟滞相关蛋白Oligophrenin-1抗体Predicted Molecular Weight: 92kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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