生长素/肥胖抑制素前激素原抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 生长素/肥胖抑制素前激素原抗体  Buffer = Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

Background:

This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the生长素/肥胖抑制素前激素原抗体 secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple生长素/肥胖抑制素前激素原抗体 transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]

生长素/肥胖抑制素前激素原抗体Also known as:

Appetite-regulating hormone; ghrelin/obestatin preprohormone; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; MTLRP; obestatin 13; Obestatin 23; obestatin-13; Obestatin-23; obestatin13; Obestatin23; GHRL_HUMAN; Protein M46.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthetic peptide derived from human Obestatin.

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生长素/肥胖抑制素前激素原抗体Predicted Molecular Weight: 2.5kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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