供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL1178R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 蛋白酶激活受体-2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The Proteinase-activated receptor 2 (PAR2) is a member of the proteinase-activated receptor subfamily. It is activated through proteolytic exposure of an occult tethered ligand by trypsin and trypsin-like proteases. This is in contrast to other members of the subfamily which are activated by the protease thrombin. PAR2 has been implicated in acute inflammatory蛋白酶激活受体-2抗体 response, asthma, and pain transmission. PAR2 expression has been documented in the periphery. ESTs have been isolated from adrenal, brain, breast, heart/melanocyte/uterus, kidney, lung, and vessel libraries.
Coagulation factor II (thrombin) receptor-like 1 (F2RL1)is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin,蛋白酶激活受体-2抗体 but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq].
Also known as:
Coagulation factor II receptor like 1; Coagulation factor II receptor-like 1; Coagulation factor II thrombin receptor like 1; F2RL1; G protein coupled receptor 11; G-protein coupled receptor 11; GPR11; PAR 2; PAR-2; PAR2_HUMAN; Protease activated receptor 2;蛋白酶激活受体-2抗体 Proteinase activated receptor 2; Proteinase-activated receptor 2; Thrombin receptor like 1; Thrombin receptor-like 1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human PAR2 (101-150aa).
●
蛋白酶激活受体-2抗体Predicted Molecular Weight: 40kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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