乳腺癌易感基因相关蛋白2

Quantity size:

0.2ml

Concentration:

1mg/ml 乳腺癌易感基因相关蛋白2  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. Essential乳腺癌易感基因相关蛋白2 partner of BRCA2 that promotes the localization and stability of BRCA2. Also enables its recombinational repair and checkpoint functions of BRCA2. May act by promoting stable association of BRCA2 with nuclear structures, allowing BRCA2 to escape the effects of proteosome-mediated degradation.

乳腺癌易感基因相关蛋白2Also known as:

DKFZp667I166; 4732427B05; BC066140; DKFZp686E1054; FANCN; FANCN GENE; FLJ21816; OTTMUSP00000025884; PALB2; partner and localizer of BRCA2; RGD1304759; PALB2_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,乳腺癌易感基因相关蛋白2 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Cow, .

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Immunogen: KLH conjugated synthetic peptide derived from human PALB2 C-terminus.

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乳腺癌易感基因相关蛋白2Predicted Molecular Weight: 131kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:20-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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