p53正向细胞凋亡调控因子抗体

Quantity size:

0.2ml

Concentration:

1mg/ml p53正向细胞凋亡调控因子抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind top53正向细胞凋亡调控因子抗体 anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

p53正向细胞凋亡调控因子抗体Also known as:

PUMA; bcl-2 binding component 3; BBC 3; BBC3; BCL 2 binding component 3; BCL2 binding component 3; JFY 1; JFY1; p53 up regulated modulator of apoptosis; p53 Upregulated Modulator of Apoptosis; PUMA alpha; PUMA/JFY1; BBC3_RAT.

Specificity:

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Rabbit Polyclonal IgG,p53正向细胞凋亡调控因子抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, .

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Immunogen: KLH conjugated synthetic peptide derived from human BBC3.

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p53正向细胞凋亡调控因子抗体Predicted Molecular Weight: 21kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:20-300  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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