磷酸化p21激活激酶2抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化p21激活激酶2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been 磷酸化p21激活激酶2抗体 implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, members of which are activated by small molecular weight GTPases. The three most common isoforms are PAK 1, PAK 2, and PAK 3 (also known as alpha PAK, gamma PAK, and beta PAK, respectively). These kinases contain numerous regulatory elements that triggerV diverse signaling processes such as those initiated by activated GTPases, interaction with Src homology 3 (SH3) domains, and caspase mediated proteolytic cleavage. Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), catalyzed by Cdc42, is required for activation of PAK.

Also known as:

PAK2 (phospho S20); PAK2 (phospho Ser20); p-PAK2 (S20); p-PAK2 (Ser20); CB422; EC 2.7.11.1; Gamma PAK; hPAK65; Kinase; p21 (CDKN1A)-activated kinase 2a; p21 activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21 protein Cdc42 Rac activated kinase 2; Vp21-activated kinase, 65-KD antibody p21-activated protein kinase I; p21CDKN1A activated kinase 2; p58; p65PAK; PAK 2; PAK65; PAKgamma; S6 H4 kinase; Serine threonine protein kinase PAK 2.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, .

●

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human PAK2 around the phosphorylation site of Ser20.

●

磷酸化p21激活激酶2抗体 Predicted Molecular Weight: 58kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl895Hu01分拣蛋白1(SORT1)多克隆抗体Polyclonal Antibody to Sortilin 1 (SORT1)

kl896Hu01皮敌菌素(DCD)多克隆抗体Polyclonal Antibody to Dermcidin (DCD)

kl896Ra01皮敌菌素(DCD)多克隆抗体Polyclonal Antibody to Dermcidin (DCD)

kl902Hu01双特异性磷酸酶1(DUSP1)多克隆抗体Polyclonal Antibody to Dual Specificity Phosphatase 1 (DUSP1)

kl902Mu01双特异性磷酸酶1(DUSP1)多克隆抗体Polyclonal Antibody to Dual Specificity Phosphatase 1 (DUSP1)

kl903Ra01碘甲腺原氨酸脱碘酶Ⅱ(DIO2)多克隆抗体Polyclonal Antibody to Deiodinase, Iodothyronine, Type II (DIO2)

kl906Hu01成纤维细胞生长因子3(FGF3)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 3 (FGF3)

kl907Hu01成纤维细胞生长因子18(FGF18)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 18 (FGF18)

kl913Hu01成纤维细胞生长因子11(FGF11)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 11 (FGF11)

kl913Mu01成纤维细胞生长因子11(FGF11)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 11 (FGF11)

kl914Hu01成纤维细胞生长因子12(FGF12)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 12 (FGF12)

kl914Mu01成纤维细胞生长因子12(FGF12)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 12 (FGF12)

kl915Hu01成纤维细胞生长因子13(FGF13)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13)

kl915Mu01成纤维细胞生长因子13(FGF13)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13)

kl918Hu01成纤维细胞生长因子21(FGF21)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

kl918Po01成纤维细胞生长因子21(FGF21)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

kl919Hu01血小板衍生生长因子D(PDGFD)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor D (PDGFD)

kl920Hu01血小板衍生生长因子C(PDGFC)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor C (PDGFC)

kl920Mu01血小板衍生生长因子C(PDGFC)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor C (PDGFC)

kl921Hu01血小板衍生生长因子B(PDGFB)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor Subunit B (PDGFB)

kl921Po01血小板衍生生长因子B(PDGFB)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor Subunit B (PDGFB)

kl921Ra01血小板衍生生长因子B(PDGFB)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor Subunit B (PDGFB)

kl922Hu01血小板衍生生长因子受体样蛋白(PDGFRL)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor Receptor Like Protein (PDGFRL)

kl922Mu01血小板衍生生长因子受体样蛋白(PDGFRL)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor Receptor Like Protein (PDGFRL)

kl923Hu01生长激素2(GH2)多克隆抗体Polyclonal Antibody to Growth Hormone 2 (GH2)

kl935Ra01促肾上腺皮质素释放激素受体1(CRHR1)多克隆抗体Polyclonal Antibody to Corticotropin Releasing Hormone Receptor 1 (CRHR1)

kl937Mu01鞘氨醇1磷酸酯受体1(S1PR1)多克隆抗体Polyclonal Antibody to Sphingosine 1 Phosphate Receptor 1 (S1PR1)