磷酸化蛋白激酶C亚性抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化蛋白激酶C亚性抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

PRKACA and PRKACB are members of the Ser/Thr protein kinase family and are a catalytic subunit of cAMP-dependent protein kinase. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive磷酸化蛋白激酶C亚性抗体 holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Several alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2011]

磷酸化蛋白激酶C亚性抗体Also known as:

Phospho-PRKACB(Thr198); Phospho-PKA alpha + beta(Thr198); PKA alpha + beta (catalytic subunits) (phospho T198); C alpha; cAMP dependent protein kinase beta catalytic subunit; cAMP dependent protein kinase alpha catalytic subunit; cAMP dependent protein kinase catalytic subunit alpha; cAMP dependent protein kinase catalytic subunit beta; Cs; PKA; PKA C; PKA C alpha; PKA C beta; PKACA; PKACB; PRKACA; PRKACB; Protein kinase cAMP dependent catalytic alpha; Protein kinase cAMP dependent catalytic beta; Protein kinase cAMP dependent catalytic beta isoform a; Protein kinase cAMP dependent catalytic beta isoform b; KAPCB_HUMAN; PKA C-beta.

Specificity:

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Rabbit Polyclonal IgG, 磷酸化蛋白激酶C亚性抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human PRKACB around the phosphorylation site of Thr198.

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Predicted Molecular Weight: 40kDa.

Storage:

磷酸化蛋白激酶C亚性抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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