供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL5010R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 磷酸化酶激酶γ2 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits 磷酸化酶激酶γ2contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
磷酸化酶激酶γ2Also known as:
GSD9C; PHK gamma LT; PHK gamma T; Phosphorylase b kinase gamma catalytic chain testis/liver isoform; Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; Phosphorylase kinase gamma subunit 2; Phosphorylase kinase subunit gamma 2; Phosphorylase kinase, gamma 2 (testis); PHKG2_HUMAN; Phosphorylase kinase, gamma 2 (testis/liver); PSK C3; Serine/threonine protein kinase PHKG2.
Specificity:
●
Rabbit Polyclonal IgG, 磷酸化酶激酶γ2 affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human PHKG2.
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Predicted Molecular Weight: 46kDa.
磷酸化酶激酶γ2Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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