蛋白质二硫键异构酶抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 蛋白质二硫键异构酶抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase蛋白质二硫键异构酶抗体 because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.

蛋白质二硫键异构酶抗体Also known as:

P4HB; Pancreas specific protein disulfide isomerase; Pancreas-specific protein disulfide isomerase; Pancreatic protein disulfide isomerase; PDA2; PDI; PDIA2; PDIA2_HUMAN; PDIP; PDIR; Protein disulfide isomerase A2; Protein disulfide isomerase; Protein disulfide isomerase associated 2; Protein disulfide isomerase family A member 2; Protein disulfide isomerase pancreatic; Protein disulfide-isomerase A2; Rho GDP dissociation inhibitor gamma.

Specificity:

●

Rabbit Polyclonal IgG,蛋白质二硫键异构酶抗体 affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, .

●

Immunogen: KLH conjugated synthetic peptide derived from human PDIA2/PDI.

●

蛋白质二硫键异构酶抗体Predicted Molecular Weight: 56kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl494Hu01弗林蛋白酶(FUR)多克隆抗体Polyclonal Antibody to Furin (FUR)

kl499Hu01间隙连接蛋白β1(GJβ1)多克隆抗体Polyclonal Antibody to Gap Junction Protein Beta 1 (GJb1)

kl500Hu01胃动蛋白1(GKN1)多克隆抗体Polyclonal Antibody to Gastrokine 1 (GKN1)

kl500Ra01胃动蛋白1(GKN1)多克隆抗体Polyclonal Antibody to Gastrokine 1 (GKN1)

kl501Hu01乙二醛酶Ⅰ(GLO1)多克隆抗体Polyclonal Antibody to Glyoxalase I (GLO1)

kl503Mu01G蛋白β1(GNβ1)多克隆抗体Polyclonal Antibody to G Protein Beta 1 (GNb1)

kl511Hu01酸性葡萄糖苷酶β(GβA)多克隆抗体Polyclonal Antibody to Glucosidase Beta, Acid (GbA)

kl513Hu01颗粒体蛋白(GRN)多克隆抗体Polyclonal Antibody to Granulin (GRN)

kl514Hu01生长因子受体结合蛋白2(Grb2)多克隆抗体Polyclonal Antibody to Growth Factor Receptor Bound Protein 2 (Grb2)

kl517Hu01透明质酸结合蛋白2(HABP2)多克隆抗体Polyclonal Antibody to Hyaluronan Binding Protein 2 (HABP2)

kl520Hu01透明质酸合酶1(HAS1)多克隆抗体Polyclonal Antibody to Hyaluronan Synthase 1 (HAS1)

kl524Hu01刺猬因子相互作用蛋白(HHIP)多克隆抗体Polyclonal Antibody to Hedgehog Interacting Protein (HHIP)

kl524Mu01刺猬因子相互作用蛋白(HHIP)多克隆抗体Polyclonal Antibody to Hedgehog Interacting Protein (HHIP)

kl534Hu01组氨酸丰富糖蛋白(HRG)多克隆抗体Polyclonal Antibody to Histidine Rich Glycoprotein (HRG)

kl534Mu01组氨酸丰富糖蛋白(HRG)多克隆抗体Polyclonal Antibody to Histidine Rich Glycoprotein (HRG)

kl536Hu01通用转录因子ⅡA肽1(GTF2A1)多克隆抗体Polyclonal Antibody to General Transcription Factor IIA, Polypeptide 1 (GTF2A1)

kl537Hu01低氧上调节因子1(HYOU1)多克隆抗体Polyclonal Antibody to Hypoxia Up Regulated 1 (HYOU1)

kl541Bo01免疫球蛋白结合蛋白1(IGBP1)多克隆抗体Polyclonal Antibody to Immunoglobulin Binding Protein 1 (IGBP1)

kl547Mu01肌苷三磷酸酶(ITPA)多克隆抗体Polyclonal Antibody to Inosine Triphosphatase (ITPA)

kl549Hu01外皮蛋白(EVPL)多克隆抗体Polyclonal Antibody to Envoplakin (EVPL)

kl551Hu01Janus激酶1(JAK1)多克隆抗体Polyclonal Antibody to Janus Kinase 1 (JAK1)

kl553Hu01角膜蛋白(KERA)多克隆抗体Polyclonal Antibody to Keratocan (KERA)