供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL5872R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 血浆激肽释放酶重链抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held 血浆激肽释放酶重链抗体together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients. [provided by RefSeq, Jul 2008]
血浆激肽释放酶重链抗体Also known as:
Plasma Kallikrein 1B; Plasma kallikrein B1; EC 3.4.21.34; Fletcher factor; Kallikrein 3 plasma (Fletcher factor); kallikrein B plasma; Kallikrein B plasma (Fletcher factor) 1; Kallikrein B, plasma 1; Kininogenin; KLK3; KLKB1; KLKB1_HUMAN; Plasma kallikrein; Plasma prekallikrein; PPK; Prekallikrein; plasma kallikrein B1 heavy chain; Plasma kallikrein; Fletcher factor; Plasma kallikrein heavy chain.
Specificity:
●
Rabbit Polyclonal IgG,血浆激肽释放酶重链抗体 affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Cow, .
●
Immunogen: KLH conjugated synthetic peptide derived from human plasma kallikrein B1 heavy chain.
●
血浆激肽释放酶重链抗体Predicted Molecular Weight: 41kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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