核糖体p70 S6蛋白激酶抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 核糖体p70 S6蛋白激酶抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads核糖体p70 S6蛋白激酶抗体to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].

核糖体p70 S6蛋白激酶抗体Also known as:

p70 S6K alpha; p70(S6K) alpha; p70-beta 1; p70-S6KA; p70S6Ka; Ribosomal protein S6 kinase 70kDa; p70 S6 kinase alpha.

Specificity:

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Rabbit Polyclonal IgG, 核糖体p70 S6蛋白激酶抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human p70 S6 kinase alpha.

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核糖体p70 S6蛋白激酶抗体Predicted Molecular Weight: 70kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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