Cyclin A1相互作用蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml Cyclin A1相互作用蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

PROCA1 is a 364 amino acid protein that belongs to the PROCA1 family and exists as two alternatively spliced isoforms. Conserved in dog, cow, mouse and rat, PROCA1 participates in calcium ion binding and phospholipase A2 activity. The gene that encodes PROCA1 maps to human chromosome 17q11.2. Chromosome 17 makes up over 2.5% of the human genome, Cyclin A1相互作用蛋白抗体with approximately 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is recognized as a genetic Cyclin A1相互作用蛋白抗体determinant of early onset breast cancer. Chromosome 17 is also linked to neurofibromatosis, dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease。

Also known as:

PRCA1_HUMAN; Proca1; proline-rich cyclin A1-interacting protein; Protein interacting with cyclin A1; Protein PROCA1; RP23-185A18.6.

Cyclin A1相互作用蛋白抗体Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human PROCA1.

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Predicted Molecular Weight: 41kDa.

Cyclin A1相互作用蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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