腺苷单磷酸活化蛋白激酶γ2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 腺苷单磷酸活化蛋白激酶γ2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

AMPK is a heterotrimeric complex comprising a catalytic a subunit and regulatory b and g subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase and inhibition of dephosphorylation. Activated AMPK 腺苷单磷酸活化蛋白激酶γ2抗体can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. The human AMPKa1 and AMPKa2 genes encode 548 amino acid and 552 amino acid proteins, respectively. Human AMPKb1 encodes a 271 amino acid protein and human AMPKb2 encodes a 272 amino acid protein. The human AMPKg1 gene encodes a 331 腺苷单磷酸活化蛋白激酶γ2抗体amino acid protein. Human AMPKg2 and AMPKg3, which are 569 and 492 amino acid proteins, respectively, contain unique N-terminal domains and may participate directly in the binding of AMP within the AMPK complex.

Also known as:

腺苷单磷酸活化蛋白激酶γ2抗体5''-AMP-activated protein kinase subunit gamma-2; AAKG; AAKG2; AAKG2_HUMAN; AMPK gamma2; AMPK subunit gamma 2; AMPK subunit gamma-2; CMH6; H91620p; Prkag2; Protein kinase AMP activated gamma 2 non catalytic subunit; WPWS.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human PRKAG2/AMPKγ2.

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腺苷单磷酸活化蛋白激酶γ2抗体Predicted Molecular Weight: 63kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl078Hu01层粘连蛋白α5(LAMα5)多克隆抗体Polyclonal Antibody to Laminin Alpha 5 (LAMa5)

kl080Hu01层粘连蛋白β2(LAMβ2)多克隆抗体Polyclonal Antibody to Laminin Beta 2 (LAMb2)

kl081Hu01层粘连蛋白β3(LAMβ3)多克隆抗体Polyclonal Antibody to Laminin Beta 3 (LAMb3)

kl083Hu01层粘连蛋白γ2(LAMγ2)多克隆抗体Polyclonal Antibody to Laminin Gamma 2 (LAMC2)

kl086Hu01Ⅰ类主要组织相容性复合体C(MHCC)多克隆抗体Polyclonal Antibody to Major Histocomklibility Complex Class I C (MHCC)

kl097Hu01整合素α11(ITGα11)多克隆抗体Polyclonal Antibody to Integrin Alpha 11 (ITGa11)

kl099Hu01整合素β6(ITGβ6)多克隆抗体Polyclonal Antibody to Integrin Beta 6 (ITGb6)

kl102Hu01骨成型蛋白3(BMP3)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 3 (BMP3)

kl105Mu01骨形成蛋白8B(BMP8B)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 8B (BMP8B)

kl106Hu01骨成型蛋白10(BMP10)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10)

kl106Mu01骨成型蛋白10(BMP10)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 10 (BMP10)

kl107Hu01骨形成蛋白15(BMP15)多克隆抗体Polyclonal Antibody to Bone Morphogenetic Protein 15 (BMP15)

kl108Hu01生长分化因子1(GDF1)多克隆抗体Polyclonal Antibody to Growth Differentiation Factor 1 (GDF1)

kl109Mu01生长分化因子3(GDF3)多克隆抗体Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3)

kl109Ra01生长分化因子3(GDF3)多克隆抗体Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3)

kl110Hu01生长分化因子5(GDF5)多克隆抗体Polyclonal Antibody to Growth Differentiation Factor 5 (GDF5)

kl113Mu01生长分化因子11(GDF11)多克隆抗体Polyclonal Antibody to Growth Differentiation Factor 11 (GDF11)

kl123Hu01Smad同源物3(Smad3)多克隆抗体Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3)

kl123Ra01Smad同源物3(Smad3)多克隆抗体Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3)

kl124Mu01Smad同源物2(Smad2)多克隆抗体Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 2 (Smad2)

kl125Hu01Cerberus蛋白(CER)多克隆抗体Polyclonal Antibody to Cerberus (CER)

kl126Ra01腱蛋白(CHRD)多克隆抗体Polyclonal Antibody to Chordin (CHRD)