钙粘蛋白相关神经受体8抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 钙粘蛋白相关神经受体8抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. These genes generate thousands of different protocadherin proteins 钙粘蛋白相关神经受体8抗体through alternative promoter usage and cis-alternative splicing. PCDHA and PCDHG family members form oligomers, which also increases the diversity of PCDH proteins at the cell surface. All three gene clusters, PCDHA, PCDHB, and PCDHG show upregulated expression during brain development, and PCDHA is subsequently downregulated by myelination. Expression of all three clusters continues in the olfactory bulb, hippocampus and cerebellum until adulthood.钙粘蛋白相关神经受体8抗体 Members of the PCDH family are potential targets in schizophrenia and bipolar disorder pathogenesis. PCDHA10 produces at least three isoforms by alternative splicing.

钙粘蛋白相关神经受体8抗体Also known as:

Cadherin related neuronal receptor 8; CNR 8; Cnr3; CNR8; CNRN 8; CNRN-8; CNRS 8; CNRS8; CRNR 8; Crnr3; CRNR8; Ortholog to mouse CNR8; PCDH alpha10; PCDHA 10; Pcdha14; PCDHALPHA10; Protocadherin alpha 10; rCNRv10; PCDAA_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, .

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Immunogen: KLH conjugated synthetic peptide derived from human PCDHA10/CNRN8.

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钙粘蛋白相关神经受体8抗体Predicted Molecular Weight: 100kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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